冷冻治疗宫颈高级别上皮内病变的临床效果观察

Clinical observation of cryotherapy for high grade intraepithelial lesions of the cervix

中文关键词: 冷冻治疗  宫颈高级别上皮内病变  临床效果

英文关键词: Cryotherapy  Cervical high lesion  Clinical effect

中文摘要:

      目的：观察冷冻治疗宫颈高级别上皮内病变的临床效果。方法：将本院收治的87例宫颈高级别上皮内病变患者随机分为两组，观察组44例采用冷冻治疗+保妇康栓治疗，对照组43例采用单纯保妇康栓治疗，比较两组的临床效果。结果：观察组、对照组总有效率分别为97.73%、72.09%，组间差异有统计学意义（P＜0.05）；观察组治疗后C反应蛋白（CRP）、肿瘤坏死因子α（TNF-α）、白细胞介素10（IL-10）、白细胞介素1β（IL-1β）改善较对照组明显，组间差异有统计学意义（P＜0.05）。结论：冷冻治疗宫颈高级别上皮内病变的临床疗效较高，血清炎性因子水平改善明显，宫颈病变治愈率高，CIN分级下降明显，具有较高的临床推广价值。

英文摘要:

      Objective:To observe the clinical effect of cryotherapy for high grade intraepithelial lesions of the cervix.Methods:Eighty-seven patients with high-grade cervical intraepithelial lesions admitted to our hospital were randomly divided into two groups.The observation group was treated with cryotherapy+Baofukang suppository,and the control group was treated with simple Baofukang suppository.The clinical effects of the groups were compared.Results:The total effective rate of the observation group and the control group were 97.73%and 72.09%,respectively.The difference between the two groups was statistically significant(P＜0.05).The C-reactive protein(CRP)and tumor necrosis factor-α(TNF-α)were treated in the observation group.The improvement of interleukin-10(IL-10)and interleukin-1β(IL-1β) was significantly higher than that of the control group,and the difference between the two groups was statistically significant(P＜0.05).Conclusion:The clinical efficacy of cryotherapy for high grade intraepithelial lesions of the cervix is high,and the serum inflammatory factor level is improved obviously,which has a high promotion value.