几类常用宫颈癌筛选技术比较和应用探究

Comparison and application of several common cervical cancer screening techniques

中文关键词: 宫颈癌  筛查  TCT联合HPV-DNA  TCT技术

英文关键词: Cervical Cancer  Screening  TCT Combined With HPV-DNA  TCT Technology

中文摘要:

      目的：对比几类常用宫颈癌筛选技术的应用情况，为临床宫颈癌筛查工作提供理论借鉴。方法：择选2017年8月至2019年8月，于本院接受宫颈癌筛查的受检者1407例为研究对象，分别对其采用TCT技术、HPV技术和TCT联合HPV-DNA进行宫颈癌筛查，并最终与病理检查结果进行对比，评价三种宫颈癌筛选方法的检出率和符合率，验证其应用有效性。结果：与病理检查结果作对比，TCT联合HPV-DNA的检出率和符合率均要高于TCT技术和HPV技术。病理检查结果显示，1407例受检者中有63例为宫颈疾病患者，检出率为4.48%，TCT联合HPV-DNA筛选结果为63例宫颈疾病患者，检出率为4.48%，符合率为100.00%，而单一TCT技术的筛选结果仅有51例宫颈疾病患者，检出率为3.62%，符合率为80.95%，差异有统计学意义（P＜0.05）。HPV技术检测出56例宫颈疾病患者，检出率为4.00%，符合率为88.89%，差异统计学有意义，P＜0.05。结论：在宫颈癌筛查中，采用TCT联合HPV-DNA可进一步提高宫颈疾病的检出率，筛选结果准确率高，具有较高的临床应用价值。

英文摘要:

      Objective:To compare the application of several common cervical cancer screening technologies and provide theoretical references for clinical cervical cancer screening.Methods:From August 2017 to August 2019,1407 patients who were screened for cervical cancer in our hospital were selected as the research subjects,and TCT technology,HPV technology,and TCT combined with HPV-DNA were used for cervical cancer.Screening,and finally comparing with the results of pathological examination,to evaluate the detection rate and coincidence rate of the two cervical cancer screening methods,to verify the effectiveness of its application.Results:Compared with the results of pathological examination,the detection rate and coincidence rate of TCT combined with HPV-DNA were higher than those of TCT and HPV.Pathological examination showed that 63 of the 1407 subjects were patients with cervical disease,the detection rate was 4.48%,and TCT combined with HPV-DNA screening results were 63 patients with cervical disease,the detection rate was 4.48%,and the coincidence rate 100.00%,and only 51 patients with cervical disease were selected by the single TCT technology.The detection rate was 3.62%,and the coincidence rate was 80.95%.The difference was statistically significant(P<0.05).HPV technology detected 56 patients with cervical disease,the detection rate was 4.00%,the coincidence rate was 88.89%,and the difference was statistically significant,P<0.05.Conclusion:In the screening of cervical cancer,the use of TCT and HPV-DNA can further improve the detection rate of cervical diseases,and the accuracy of the screening results is high,which has high clinical application value.