硫酸镁联合硝苯地平治疗妊娠高血压的效果分析

Effect of magnesium sulfate combined with nifedipine on pregnancy induced hypertension

中文关键词: 硝苯地平  硫酸镁  妊娠高血压

英文关键词: Nifedipine  Magnesium sulfate  Pregnancy hypertension

中文摘要:

      目的：探讨硫酸镁联合硝苯地平治疗妊娠高血压的效果。方法：研究对象均为本院收治妊娠高血压患者共94例，采用单双号随机抽签的方式分组实施研究，每组各47例，其中抽取到单号的患者纳入对照组，单纯给予硫酸镁治疗，另外一组抽取的全部为双号，纳入观察组采用联合硝苯地平治疗的方式，对比两组治疗前后血压水平、血黏度、24h尿蛋白量及分娩结局。结果：治疗前，两组患者的血压水平经过SPSS 20.0软件系统分析显示无差异（P＞0.05）；治疗后，两组患者的血压水平经过SPSS 20.0软件系统分析显示显著下降，且观察组下降幅度更大（P＜0.05）；与对照组比较，观察组患者血黏度及24h尿蛋白量显著更低（P＜0.05）。结论：针对妊娠高血压患者，硫酸镁联合硝苯地平的治疗方案能起到良好的稳定血压效果，使得产妇的血黏度及24h尿蛋白量均得以降低。

英文摘要:

      Objective: To investigate the effect of magnesium sulfate combined with nifedipine on pregnancy induced hypertension. Methods: The subjects were all pregnant hypertensive 94 cases, using single and double random draw, 47 cases per group, the patients with single number were included in the control group, mere magnesium sulfate treatment. The other group was drawn with double numbers, and the observation group was included in the combined treatment with nifedipine. The blood pressure level, blood viscosity, 24h urine protein amount and delivery outcome were compared between the two groups before and after treatment. Results: Before treatment, the blood pressure level of the two groups was analyzed by SPSS 20.0 software system (P＞0.05); After treatment, blood pressure levels in both groups were significantly reduced by SPSS 20.0 software system analysis, and the observation group decreased more (P＜0.05); Compared with the control group, The blood viscosity and 24h urine protein in the observation group were significantly lower (P＜0.05). Conclusion: For hypertensive patients with pregnancy, magnesium sulfate combined with nifedipine can stabilize blood pressure, blood viscosity and 24h urine protein were reduced.